Researcher Essentials
Join the Effort
Register for access to the N3C Data Enclave and explore harmonized clinical data within a secure analytics platform.
Researchers are welcome to request access to the N3C Data Enclave, a leading secure data resource designed to support and accelerate collaborative research across a wide range of health topics. Users may also join or start an N3C Domain Team to help coordinate work with others. If you experience difficulty at any stage in your enclave journey, please visit the N3C Support Desk.
Gain Access to the Enclave
- Complete the Enclave Registration Checklist to expedite your N3C Data Enclave account creation.
- Follow the Enclave Registration Instructions to request and access your enclave account. During the process of creating your enclave account, you will also complete your N3C registration. You can update your profile information anytime here.
Domain Teams
N3C Domain Teams bring together researchers with shared clinical questions to collaboratively analyze data within the N3C Data Enclave, fostering efficient teamwork and accelerating discoveries across various health topics.
Learn More
Required Governance Documents
- The Data Use Agreement (DUA) is a legal document that covers the terms of how data are accessed or used within the N3C Data Enclave. It is executed between NCATS and a research institution (or directly with a researcher in the case of an individual citizen scientist who is not affiliated with an institution). This agreement covers the contributing site’s use of the data for research. Signing of the DUA and IRB approval are both required to use data in the N3C Data Enclave.
- See the list of institutions with active DUAs
- A Data Use Request (DUR) is an electronic application submitted within the N3C Data Enclave by the researcher to describe the scope and nature of their work and to justify the data access tier they are requesting. Approved DURs are valid for 1 year and are renewable. Learn more about the online Data Use Request (DUR) process here.
To Cite the N3C: "The analyses described in this [publication/report/presentation] were conducted with data or tools accessed through the NCATS N3C Data Enclave https://covid.cd2h.org and N3C Attribution & Publication Policy v 1.2-2020-08-25b supported by NCATS Contract No. 75N95023D00001 and [insert additional funding agencies or sources and reference numbers as declared by the contributors in their form response above]. This research was possible because of the patients whose information is included within the data and the organizations (https://ncats.nih.gov/n3c/resources/data-contribution/data-transfer-agreement-signatories) and scientists who have contributed to the on-going development of this community resource [https://doi.org/10.1093/jamia/ocaa196]."
For publication submission information, please see the Publication Review Page