We are facing an unprecedented time with the challenges of the COVID-19 pandemic. This global emergency raises many difficult questions, such as: who is infectious, who may need hospital care and at what level, what are the key risk factors, what are the best prognosis indicators, what are the best practices for ethical resource allocation, and which drugs are the most viable candidates for patients.

To help address these questions, the National Center for Data to Health (CD2H) and the National Center for Advancing Translational Science (NCATS) are creating a centralized, secure portal of COVID-19 clinical data. This initiative is a partnership among several HHS agencies, the CTSA program, and the distributed clinical data networks PCORnet, OHDSI, ACT/i2b2, and TriNetX. To minimize the effort required by network partners, NCATS will accept data from multiple data models and transform them into a common analytic model. The cloud-based collaborative portal will allow for the development of machine learning and other informatics tools that require a large row-level dataset, and will be overseen by a data access committee.

We believe this portal will provide additional assets needed to rapidly develop the analytics that clinical centers and physicians need now.


“The coronavirus pandemic has spurred us to build, for the first time, a process for collecting and harmonizing electronic health records from many different institutions, storing it in one secure location, and making it available in a collaborative platform for use by diverse experts.”

-Melissa Haendel, PhD, N3C’s lead investigator

Scripps Research Press Release

NIH Press Release

OHSU Press Release


N3C Agency Parthers