This dashboard breaks down the counts of COVID+ patients prescribed Sotrovimab by vaccination status, the occurrence of other comorbidities in relation to prescription, severity, and demographics.
Data as of Oct 10, 2024 (v185)
Patients That Received Sotrovimab* |
Sample: COVID+ patients , or patients who have had, a laboratory-confirmed positive COVID-19 PCR or Antigen test, a laboratory-confirmed positive COVID-19 Antibody test, or a Medical visit in which the ICD-10 code for COVID-19 (U07.1) was recorded in the N3C Data Enclave whose patient records included Sotrovimab on any date included within the Enclave. Data aggregated by Age, Sex, and Severity. Medications were aggregated based on ingredient included in the medication. For additional information, see limitations below
This data contains COVID+ patients within the Enclave who have evidence of each medication of interest indicated in their EHR.
A medication exposure is defined as any occurrence of a medication name or related ICD-10 code within a patient's EHR.
A Charlson Comorbidity Index (CCI) Score is calculated by identifying any CCI comorbidity attached to a medical visit within a patient’s EHR and weighing each comorbidity by its associated category. The sum of all the weights results in a single comorbidity score. More details on the CCI and its 17 associated comorbidities can be found here.
A COVID-positive patient is defined as any patient having one of the following within their EHR records:
Severity of COVID-19 is a calculation based on multiple events recorded in a patient's EHR during their medical visit. The severity score for each patient may be inaccurate due to missing information within the EHR. Patients will only be graded on Severity if they have a laboratory-confirmed positive PCR or Antigen test. Below are the definitions of each Severity Category.
The age of each patient is calculated as of the date of the last data update.
The race and ethnicity of patients are adjusted to standard categories based on self-reported fields within the EHR.
The sex of patients is determined based on self-reported fields within the EHR.
Vaccination data in the N3C is sparse and represents only EHR-recorded vaccination events at our data partners. The absence of a vaccination record does not mean that a patient is unvaccinated. If a patient were vaccinated at their local pharmacy, doctor's office, or state/federal vaccination site, they would not be represented because these systems do not automatically link to a patient's EHR.
Given the known national vaccination rates, it is likely that many, if not most, vaccination events are occurring outside of the academic health systems submitting data. Therefore, patients shown here as "Unknown" may be vaccinated; however, we do not have the records to verify this.
Vaccinated patient counts shown here does not mean the patient is fully vaccinated. We consider a vaccinated patient to have at least one dose of Pfizer, Moderna, or Johnson & Johnson COVID-19 vaccines. Given that Pfizer and Moderna require two vaccine doses to be considered fully vaccinated, patients shown here may be partially vaccinated. This same assumption applies to booster shots, as we do not consider shots beyond the first one recorded within the patient's EHR.
General Enclave Limitations